Emulsification

Perfect control of droplet production

The Secoya technology is based on the integration of the most efficient microfluidic technologies in a robust stainless-steel equipment.

The way we produce droplets and particles relies on the use of couples of capillaries perfectly aligned in a metallic reservoir. The first capillary is terminated with a 3D-printed nozzle and injects the droplet phase in the junction. The second one is the only output of the system, so it collects both phases, the droplet phase and the continuous phase filling the reservoir under pressure.

The droplets are produced by the controlled squeezing of the droplet phase by the continuous phase at the entrance of the collection capillary.

emulsification2

Robust and reliable technology

This unique integration of a microfluidic technology in a robust device allows us to produce droplets and particles with the key benefits of both worlds: a high control of the size and a robust long-run production process.

  • Particle size : 10 to 200 µm
  • Size distribution : dispersity <2%
  • High frequency : > 1000 droplets per second (kHz) per injector
  • Surfactant free : no need of surfactant
  • Robustness : as no coating is required inside the capillaries, compatibility with long-run production
  • Scalability : through number-up
  • API encapsulation efficiency : >95 % (e.g. in PLGA)
  • Encapsulation versatility : both hydrophobic and hydrophilic ingredients can be encapsulated using the same technology

Up to and industrial scaling-up

  • The scaling up is achieved through the numbering-up of the injectors inside a chamber first (base unit), and then through the numbering-up of the base unit. Depending on the fluids properties, a module containing 100 injectors has the potency to reach an annual capacity of 1000 L of particles.
  • Adapted for decentralized production through easy and consistent duplication
PLGA particules web

Many applications in the encapsulation field

  • Particle size : 10 to 200 µm
  • Size distribution : dispersity <2%
  • High frequency : > 1000 droplets per second (kHz) per injector
  • Surfactant free : no need of surfactant
  • Robustness : as no coating is required inside the capillaries, compatibility with long-run production
  • Scalability : through number-up
  • API encapsulation efficiency : >95 % (e.g. in PLGA)
  • Encapsulation versatility : both hydrophobic and hydrophilic ingredients can be encapsulated using the same technology